Santon Diprenilasi dari Kayu Akar Garcinia tetranda Pierre

Fuji Ridha Kharomah, Taslim Ersam
Submission Date: 2015-08-12 08:35:06
Accepted Date: 2016-01-21 12:25:50

Abstract


Garcinia tetranda merupakan salah satu spesies dari famili Clusiaceae yang mengandung senyawa metabolit sekunder. Senyawa golongan santon telah berhasil diisolasi dari fraksi S ekstrak etil asetat kayu akar Garcinia tetranda Pierre. Senyawa golongan santon ini adalah α-mangostin 1 yang berupa padatan kuning dengan titik leleh 173-1740C. Metode isolasi yang digunakan yaitu Kromatografi Cair Vakum (KCV) menggunakan silika gel 60 GF254 dan dielusi dengan peningkatan kepolaran pelarut. Penentuan struktur senyawa dilakukan menggunakan analisis UV, IR, 1H dan 13C NMR, DEPT 135, korelasi HSQC dan HMBC serta dibandingkan dengan literatur.

Keywords


Garcinia tetranda Pierre; Santon

References


Poewardaminta, W. J., (1990), "Kamus Besar Bahasa Indonesia",Balai Pustaka

Kosela., (1999), "Penggalian Sumber Bahan Baku Obat dari Tumbuhan, Prosiding Seminar Kimia Bahan Alam, Universitas Indonesia, Jakarta

Lukis, P. A. dan Ersam, T., (2010), "Dua Senyawa Mangostin Dari Ekstrak N-Heksana Pada Kayu Akar Manggis (Garcinia mangostana, Linn) Asal Kab. Nganjuk, Jawa Timur", Prosiding Tugas Akhir Semester Genap 2010/2011, Institut Teknologi Sepuluh Nopember, Surabaya

Ersam, T., (2005), "Pemberdayaan Keanekaragaman Hayati Hutan Tropika : Fenolat Terprenilasi dari Autocarpus dan Garcinia (Nangka dan Manggis)", Prosiding Seminar Nasional Kimia (hal. 22-23), Universitas Negeri Surabaya, Surabaya

Sumaryono, W., (1999), "Produksi Metabolit Sekunder Tanaman Secara Bioteknologi", Prosiding Seminar Nasional Kimia Bahan Alam 1999, Penerbit Universitas Indonesia, Jakarta

Heyne, K., (1987). "Tumbuhan Berguna Indonesia", Yayasan Sarana Wana Jaya, Jakarta

Peres, V. dan Nagem, T. J., (1997), "Trioxygenated Naturally occuring Xanthones", Phytochemistry, 44, 191-214.

Permana, D., Lajis, N., Mackeen, M., Ali, A. M., Aimi, N. dan Kitajama, M., (2001), "Isolation and Bioaktivities of Constituents of the Roots of Garcinia atroviridi", J. Nat. Prod, 64, 976-979

Riyanto, A., (2006), "Isolasi dan Uji Bakterial Senyawa Santon dari Kayu Akar Garcinia tetranda Pierre", Tesis, Program Studi Magister Kimia, Jurusan Kimia, FMIPA, Institut Teknologi Sepuluh Nopember

Jung, H. A., Su, B. N., Keller, W. J., Metha, R.G. dan Kinghorn, A. D., (2006), “Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen)”, J. Agric. Food Chem, 54, 2077-2082

Nilar, Nguyen, L. D., Venkataraman, G., Sim, K. Dan Harrison, L. J., (2005), “Xanthones and Benzophenones from Garcinia griffithii and Garcinia mangostana”, Phytochemistry, 66, 1718-1723

Tanaka, N., Takaishi, Y., Shikishima, Y., Nakanishi, Y., Bas, Bastow, K., (2004), "Prenylated benzophenones and xanthones from Hypericum ascyron", J. Nat. Prod, 63, 1870-1875.

Supratman, U., (2010), “Elusidasi Struktur Senyawa Organik”, Widya Padjadjaran, Bandung

Ito C., Miyamoto Y. dan Kawai M. D., (1997), “A novel depsidone and some new xanthones from Garcinia spesies", Chem. Pharm. Bull, 45, 1403-1413

Sen, A. K., Saukar, K. K., Majumdu, P. C., Banerji, N., (1982), "Garcinon D, A New Xanthone from Garcinia mangostana, Linn", Indian Journal of Chemistry, 25B, 1157-1158

Riswiyanto, (2009), “Kimia Organik”. Erlangga, Jakarta

Nedialkov, P. T. dan Kitanov, G. M. Bennet, G, J., Lee, H. dan Lee, L., (1990), “Synthesis of Minor Xanthone from Garcinia mangostana”, J. Nat. Prod, 55, 1463-1470

Bennet, G, J., Lee, H. dan Lee, L., (1990), “Synthesis of Minor Xanthone from Garcinia mangostana”, J. Nat. Prod, 55, 1463-1470

Niu, S., Zhan, L., Fen, J., Gu-Yue, L. dan Nan, Z. (2012). Xanthones from the stem bark Garcinia bracteata with growth inhibitory effects against HL-60 cells. Phytochemistry, 77, 280-286

Michel, T., Destandau, E., Fougere, L. And Elfakir, C., (2012), “New “hyphenated” CPC-HPLC-DAD-MS strategy for simultaneous isolation, analysis and identification of phytochemicals: application to xanthones from Garcinia mangostana”, Anal Bioanal Chem 404:2963–2972

Astuti, S. E., (2005), "Dua Diprenilsanton pada Kulit Batang Wadung (Garcinia tetranda Pierre)", Skripsi, ITS, Surabaya


Full Text: PDF

CC Licencing


Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Refbacks

  • There are currently no refbacks.


Lembaga Penjaminan Mutu, Pengelolaan dan Perlindungan Kekayaan Intelektual (LPMP2KI) ITS
Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.