Isolasi Senyawa Artobiloksanton dari Kulit Akar Artocarpus elasticus

Amalia Zafitri, Taslim Ersam
Submission Date: 2016-06-29 08:44:18
Accepted Date: 2016-11-23 18:14:55

Abstract


Artocarpus kaya akan senyawa fenolat salah satunya adalah flavonoid. Senyawa ini memiliki sifat bioaktivitas dan telah lama digunakan sebagai sumber pengobatan tradisional di Indonesia. Penelitian ini bertujuan untuk mengisolasi senyawa flavonoid dari kulit akar Artocarpus elasticus yang berasal dari Pulau Alor, Nusa Tenggara Timur (NTT). Proses ekstraksi dilakukan dengan metode maserasi menggunakan pelarut metilen klorida dan dilanjutkan dengan metode fraksinasi menggunakan Kromatografi Cair Vakum (KCV). Pemurnian dilakukan dengan metode rekristalisasi. Penentuan struktur senyawa dilakukan menggunakan analisis UV, IR, 1H dan 13C NMR. Senyawa yang berhasil diisolasi yaitu artobiloksanton (1) berupa padatan coklat muda dengan titik leleh 211-212°C yang merupakan senyawa yang telah dilaporkan pada penelitian sebelumnya.


Keywords


Moraceae; Artocarpus elasticus; Artobiloksanton

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