Isolasi Senyawa 3β-asetoksi-lup-20(29)-en-2-ol dan Uji Antioksidan dari Tumbuhan Kepulauan Aru (Sonneratia ovata Backer)

Fatmawati Inneke Putri, Taslim Ersam, Sri Fatmawati
Submission Date: 2016-08-01 09:36:45
Accepted Date: 2016-11-23 18:14:55

Abstract


Sonneratia ovata Backer merupakan salah satu tanaman yang berasal dari Kota Dobo, Kepulauan Aru. Senyawa 3β-asetoksi-lup-20(29)-en-2α-ol (1) berupa serbuk putih dengan titik leleh 200-201oC berhasil diisolasi dari ekstrak metanol kulit batang Sonneratia ovata Backer. Senyawa tersebut difraksinasi menggunakan metode kromatografi cair vakum (KCV) dan kromatografi kolom gravitasi (KKG). Senyawa murni diidentifikasi menggunakan spektroskopi IR, 1H-NMR, dan 13C-NMR. Uji bioaktivitas antioksidan dilakukan dengan metode DPPH. Fraksi dari senyawa (1) menunjukan prosentase penghambatan sebesar 20,91 ± 0,006 %.


Keywords


Sonneratia ovata Backer; Antioksidan; Isolasi; Bahan alam; DPPH radikal

References


Mao, L., & Foong, S. Y. (2013). Tracing ancestral biogeography of Sonneratia based on fossil pollen and their probable modern analogues. 133-143.

Wu, S.-B., Wen, Y., Li, X.-W., Zhao, Y., & Hu, J.-F. (2009). Chemical constituents from the fruits of Sonneratia caseolaris. Biochemical Systematics and Ecology , 1-5.

Jariyah, Widjanarko, S. B., Yunianta, & Estiasih, T. (2014). Hypoglycemic effect of Pedada (Sonneratia caseolaris) Fruit. 31-40.

Tiwari, A. K., Viswanadh, V., Gowri, P. M., Ali, A. Z., Radhakrishnan, S., Agawane, S. B., et al. (2010). Oleanolic acid - an a-Glucosidase inhibitory and antihyperglycemic active compound from the fruits of Sonneratia caseolaris. 19-23.

Hou, W., Li, Y., Zhang, Q., Wei, X., Peng, A., Chen, L., et al. (2009). Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors. 614-618.

Sadhu, S. K., Ahmed, F., Ohtsuki, T., & Ishibashi, M. (2006). Flavonoids from Sonneratia caseolaris. 264-265.

Rouessac, F., & Rouessac, A. (1994). Chemical Analysis "Modern Instrumentation Methods and Techniques" Second Edition. England: John Wiley & Sons Ltd.

Shahlaei, M., Ghanadian, S. M., Ayatollahi, A. M., Mesaik, A. M., Abdalla, O. M., Afsharypour, S., et al. (2013). Molecular modeling, structure activity relationship and immunomodulatory properties of some lupeol derivatives. Med Chem Res , 22:1795-1803.

Rungsimakan, S., & Rowan, M. G. (2014). Terpenoids, flavonoids and caffeic acid derivatives from Salvia viridis L. cvar. Blue Jeans. Phytochemistry , 177-188.


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